Me personally? I’ve become much less tolerant of sexist humor. Back in the day, cracking a joke at women’s expense was pretty common when I was a teen. As I’ve matured and become aware to the horrific extent of toxicity and bigotry pervading all tiers of our individualistic society, I’ve come to see how exclusionarly and objectifying that sort of ‘humor’ really is, and I regret it deeply.
We still use it in English for the original purpose. If I told a native UK/AU/NZ English speaker the horse was shot after a race because it was lame, people wouldn’t assume it was because the horse was uncool.
I think lame might get more of a pass because it’s very rarely used to describe people any more, so there is a bigger disconnect.