I took my first dose of semaglutide last night. It’s only 5 units for the first month, then 10 units the 2nd month, then 20 units after that. I was scared to inject myself but it didn’t hurt! It didn’t sting like a flu shot does. I was given anti nausea medicine but didn’t need to take it. Today my appetite hasn’t been very different. I assume my appetite will change over the next 12 weeks. I’m looking forward to trying this for awhile, and hoping for results.