I am currently playing as Ifan, and have chosen Sebille, Fane and The Red Prince as my companions.
I chose Ifan as my character simply because a lone wolf seemed to be someone I wouldn’t choose as a companion.
Sebille had this very interesting introduction with the needle. That was quite something. Also, her volunteering to be in the camp for revenge is exciting.
Fane was incredibly fun on the boat. Just reading his book not caring about anything else. Also the fact that he is secretly undead is very interesting.
And The Red Prince - I honestly don’t know. He just appears to be a fun guy.
How about you?
All I know is that back then when I was still using reddit, everyone in the DoS2 sub warned to not use fextralife builds, saying they were bad builds. I went with builds by Lost Sinner from the guide section on Steam. Those builds work well. For new players I also recommend Lost Sinners walk-through guide, it helped me to jump right into the game.