For Pork Shoulder, I found Michael Rhulmans recipe to be pretty versitile:

To cook the pork, as noted in post: Ideally, sear it hard over coals in the Weber, covered for 20 to 30 minutes, then put it in a Dutch oven, covered, for 6 hours at 250 degrees (or 4 hours at 300˚F). I think smoke is critical, but if you want to make it super easy on yourself, put the raw shoulder in a Dutch oven and roast it covered at 225 overnight and that’ll do the trick as well. Stir in the sauce. Taste for seasoning—salt, sweetness, acidity,heat. Adjust as you wish