The manufacturing process of snus differs from that of other oral tobacco products. Snus tobacco is heated and pasteurized rather than cured or fermented, resulting in a less harmful product which contains a lower concentration of TSNA carcinogens in comparison to other traditional tobacco products.[2] Though research on the connection between snus and disease such as cancer is not conclusive, no associations between snus consumption and an increased risk of cancer have been found.[3]

The warning text “causes cancer” was removed from snus packaging in Sweden and other countries because current scientific evidence indicates that the cancer risk associated with snus is significantly lower than that of smoking. The shift in labeling aims to provide accurate information while still cautioning consumers about potential health concerns.

Nicotine products in general have been linked to reproductive harms such as stillbirth, premature birth, and low birth weight.[4] Conversely, non-tobacco-based nicotine pouches (also known as “nic pouches”) are classified as non-carcinogenic[5][6][7] since nicotine itself is not a carcinogen. However, they are still harmful to cardiovascular health due to their nicotine content, and are associated with moderately higher risk of cardiovascular disease, stroke, and reproductive harms.[8][9] The main causes for mortality from smoking including cardiovascular disease from the effects of smoke on vascular coagulation and blood vessel walls are not caused primarily by nicotine and hence not to be considered equal to the moderate cardiovascular health risks from nicotine pouches.[10]

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    5 days ago

    https://pmc.ncbi.nlm.nih.gov/articles/PMC4553893/

    Thus, although the level of NNK in the Swedish snus is much lower than in the old type of snuff and in cigarette smoke (16), the level of total NNAL (a NNK metabolite) in urine from users of Swedish snus is still considerable, and only reduced to about half of that found in smokers and in users of old type snuff (Table 1).

    Increased risks of cancer-specific death were observed both among exclusive smokers (HR = 1.15, 95% CI: 1.10–1.21) and never-smoking snus users (HR = 1.15, 95% CI: 1.05–1.26).

    Exclusive snus users also had increased risks for both prostate cancer mortality (HR = 1.24, 95% CI: 1.03–1.49) and total mortality (HR = 1.19, 95% CI: 1.04–1.37). The authors concluded that the results suggest that nicotine may promote cancer progression independent of the combustion products of tobacco smoke.