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Cake day: March 3rd, 2024

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  • Pretty amazing your father checked all those boxes, and then still developed dementia… My condolences… Just an absolutely horrible disease. Out of curiosity did you ever learn your father’s apoe3 based risk “adjustment” for lack of the correct term? (No pressure to share and certainly no pressure to reveal what that testing came up with) The fact that your father took such good care of himself, exercised his brain, and still developed dementia makes me think there truly must be strong genetic predisposition(s) for it as well. But it’s also scary to think of how many unaccounted-for deaths might actually be ultimately attributable to things like the Blitz and wwii.

    Side question- Do/did you ever come to feel confident you could truly narrow it down to one most likely culprit for causing the dementia? I myself lost a parent to alz, and have come to lay the blame on a handful of different possibilities (although truth be told they could all be sort of summarized by something like late stage capitalism or capitalist alienation, or something. I wonder how relatable it is to waffle around endlessly between thoughts that “this is what probably most contributed to it… no this… (months/years later) no this

    It’s rough not being able to point to what truly, certainly went wrong and caused such suffering.


  • These kinds of well-needed comments full of doubts and questions of what all was controlled for in the research and whether confounding variables remained, the kinds that always come up on reddit and now (hooray!!) lemmy, make me wonder whether research could in some cases be dramatically improved by letting the internet loose on the research hypothesis ahead of time instead of once the paper is published.

    Scientists: “In our study, we will evaluate whether a is correlated with an increase in b. We will control for w, y, x, and z.

    The internet/reddit/lemmy: “You absolute imbeciles. Did it not occur to you to control for α, β, and gamma through omega?!

    Scientists: well, we will certainly consider all those and do our best to do so now!