As someone who recently weaned off of SSRIs after several years on them, I found that thre worked quite well for managing my (at the time I was prescribed) debilitating OCD. That combined with occasional weed edibles (1-4 times a month) seems to have permanently decreased my symptoms, to the point where I no longer need SSRIs. I’ve generally heard that they work much better when applied to anxiety disorders than for depression, which makes me wonder why they’re still prescribed so often for that. My guess is some combination of institutional inertia + minor symtom improvement + profit incentive.
It’s a bit of a shot in the dark here, but have you considered looking into psychedelics? If you’re careful with them I’ve heard they can be life changing for treatment resistant depression and addiction. I only have experience with high thc cannabis (infrequently but at somewhat regular intervals, 1-4 times a month), but even that’s helped me (not in an assimilation into capitalism kind of way but in a feeling less burdened by the world kind of way, freer to pursue community, relationsips, etc, with less fear)
Even if you keep it in mind as a last resort, it might be something to consider.
Alternately/concurrently perhaps look into philosophy like that of Mark Fisher, bell hooks, or Lacan/Zizek for more perspectives from people trying to make sense of our current social reality.